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U.S. Route 321 Business (Winnsboro, South Carolina)

U.S. Route 321 marker

U.S. Route 321
Route information
Auxiliary route of US 21
Length 516.9 mi (831.9 km)
Existed 1931 – present
Tourist
routes
Western York Scenic Byway
Major junctions
South end US 17 in Hardeeville, SC
 
North end I-40 / SR 73 / SR 95 near Lenoir City, TN
Location
States South Carolina, North Carolina, Tennessee
Counties SC: Jasper, Hampton, Allendale, Bamberg, Orangeburg, Lexington, Richland, Fairfield, Chester, York
NC: Gaston, Lincoln, Catawba, Burke, Caldwell, Watauga, Avery
TN: Carter, Washington, Greene, Cocke, Sevier, Blount, Loudon
Highway system


SC 319 SC SC 322
US 311 NC NC 343
SR 320 TN SR 321

North Carolina Highway 17
Location Propst CrossroadsBoone, NC
Length 55.9 mi (90.0 km)
Existed 1921–1934

North Carolina Highway 155
Location DallasConover, NC
Length 29.4 mi (47.3 km)
Existed 1994–1999

U.S. Route 321 Business
Location Winnsboro, South Carolina
Length 4.2 mi (6.8 km)
Existed 1952–present

U.S. Route 321 Business
Location Chester, South Carolina
Length 3.7 mi (6.0 km)
Existed 1964–present

U.S. Route 321 Business
Location York, South Carolina
Length 2.5 mi (4.0 km)
Existed 1958–present

U.S. Route 321 Business
Location DallasHickory, NC
Length 37.2 mi (59.9 km)
Existed 1999–present

U.S. Route 321A
Location Lincolnton, North Carolina
Length 3.4 mi (5.5 km)
Existed 1956–1960

U.S. Route 321A
Location Granite FallsLenoir, NC
Length 11.8 mi (19.0 km)
Existed 1948–present

U.S. Route 321A
Location Lenoir, North Carolina
Length 5.9 mi (9.5 km)
Existed 1941–1948

U.S. Route 321 marker

U.S. Route 321 (US 321) is a spur of U.S. Route 21. It runs for 516.9 miles (831.9 km) from Hardeeville, South Carolina to Lenoir City, Tennessee; with both serving as southern termini. It reaches its northernmost point at Elizabethton, Tennessee. Because of its unusual "north–south–north" routing, U.S. Route 321 intersects both Interstate 40 and U.S. Route 70 three separate times. The highway serves different roles in each state: An alternate route to interstates in South Carolina, a major highway in North Carolina, and a scenic route in Tennessee.

U.S. 321 provides direct access between Savannah and Columbia, serving as an alternate to Interstate 95 and Interstate 26. Starting in Hardeeville, U.S. 321 as a mostly 2 lane highway goes through sparsely populated areas and small towns including Estill, Fairfax, and Denmark, heading in a rather straight and northward direction into the Columbia area, widening to a 5 lane highway right after Neeses, then narrowing down to a 2 lane highway right after the town of North and widening to a 5 lane highway again after Swansea and staying that way until it merges with its parent route U.S. 21 in Dixiana. In Columbia, the route stays concurrent with U.S. 21 through Cayce, over the Congaree River on the Blossom Street Bridge, turning left onto Huger Street, right onto Elmwood Avenue, and left onto North Main Street. The roads separate at Hyatt Park, with U.S. 321 staying west of Interstate 77 and U.S. 21 north of Columbia. The route goes through to communities of Winnsboro, Chester, York, and Clover before entering North Carolina at Bowling Green.


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