Gran Colombia (Spanish pronunciation: [ˈɡɾaŋ koˈlombja], "Great Colombia") is a name used today for the state that encompassed much of northern South America and part of southern Central America from 1819 to 1831. It included the territories of present-day Colombia, Venezuela, Ecuador, Panama, northern Peru, western Guyana and northwest Brazil.
The first three were the successor states to Gran Colombia at its dissolution. Panama was separated from Colombia in 1903. Since Gran Colombia's territory corresponded more or less to the original jurisdiction of the former Viceroyalty of New Granada, it also claimed the Caribbean coast of Nicaragua, the Mosquito Coast.
Its existence was marked by a struggle between those who supported a centralized government with a strong presidency and those who supported a decentralized, federal form of government.
At the same time, another political division emerged between those who supported the Constitution of Cúcuta and two groups who sought to do away with the Constitution, either in favor of breaking up the nation into smaller republics or maintaining the union but creating an even stronger presidency. The faction that favored constitutional rule coalesced around Vice-President Francisco de Paula Santander, while those who supported the creation of a stronger presidency were led by President Simón Bolívar. The two men had been allies in the war against Spanish rule, but by 1825, their differences had become public and were an important part of the political instability from that year onward.