U.S. Route 52 in Indiana

U.S. Route 52
Route information
Length:	2,072 mi (3,335 km)
Existed:	1926 – present
Major junctions
West end:	Hwy 39 at Portal, ND
	I‑94 in Jamestown, ND I-35W in Minneapolis, MN I-35E in St. Paul, MN I‑90 in Rochester, MN I‑80 / I‑55 near Joliet, IL I‑65 near Lebanon, IN I‑69 / I‑70 in Indianapolis, IN I‑71 / I‑74 / I‑75 in Cincinnati, OH I‑40 in Winston-Salem, NC I‑85 in Lexington, NC I‑95 near Florence, SC
South end:	Broad Street in Charleston, SC
Location
States:	North Dakota, Minnesota, Iowa, Illinois, Indiana, Ohio, West Virginia, Kentucky, Virginia, North Carolina, South Carolina
Highway system
United States Numbered Highway System List Special Divided Replaced

U.S. Route 52 (US 52) is a United States highway that runs across the northern, eastern and southeastern regions of the United States. Contrary to most other even-numbered U.S. Highways, US 52 primarily follows a northwest–southeast route, and is signed north–south or east–west depending on the local orientation of the route.

The highway's northwestern terminus is at Portal, North Dakota, on the Canadian border, where it continues as Saskatchewan Highway 39. The southeastern terminus of US 52 is in Charleston, South Carolina, at Number 2 Meeting Street and White Point Gardens along the Charleston Harbor.

In North Dakota, US 52 continues from Highway 39 from the Canada–United States border at North Portal, Saskatchewan and Portal, North Dakota to the Red River in Fargo, a distance of 361 miles (581 km). US 52 passes through Burke, Ward, McHenry, Pierce, Sheridan, Wells, Foster, Stutsman, Barnes, and Cass counties.

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Wikipedia