South Carolina Highway 72
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| Route information | ||||
| Maintained by SCDOT | ||||
| Length: | 124.8 mi (200.8 km) | |||
| Existed: | 1942 – present | |||
| Major junctions | ||||
| West end: |
 SR 72 at the GA line near Calhoun Falls
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   US 25 / US 178 / US 221 in GreenwoodUS 221 near Cross Hill US 76 in Clinton I-26 in Clinton  US 176 / SC 121 in Whitmire  US 321 / SC 9 in Chester
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| East end: |
 SC 122 in Rock Hill
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| Location | ||||
| Counties: | Abbeville, Greenwood, Laurens, Newberry, Union County, Chester, York | |||
| Highway system | ||||
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| Location: | Greenwood, South Carolina |
| Length: | 4.2 mi (6.8 km) |
| Existed: | 1961–present |
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| Location: | Clinton, South Carolina |
| Length: | 3.3 mi (5.3 km) |
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| Location: | Chester, South Carolina |
| Length: | 2.6 mi (4.2 km) |
| Existed: | 1954–N/A |
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| Location: | Rock Hill, South Carolina |
| Length: | 1.8 mi (2.9 km) |
| Existed: | 1950–N/A |
South Carolina Highway 72 (SC 72) is a 125-mile (201 km) state highway, traversing interior portions of the South Carolina Piedmont region. The route connects many smaller communities outside major metropolitan areas and is roughly parallel with Interstate 85 to the north and interstates 20 and 77 to the south and east. The route shares the longest concurrency in the state with SC 121, from Whitmire and Rock Hill.
The route travels across the state in a southwest to northeast direction, and is sometimes referenced as an unofficial border between the Midlands and the Upstate regions. Beginning at the Georgia state line on a bridge over Lake Russell (where it is the continuation of SR 72) SC 72 goes through the town of Calhoun Falls and goes through rural areas of Abbeville County before skirting the county seat of Abbeville on a bypass route. The route serves as the major thoroughfare for traffic between Abbeville and Greenwood, where it bypasses the downtown area to the north.
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Wikipedia