Oculogyric crisis

Oculogyric crisis
Classification and external resources
Specialty	ophthalmology
ICD-10	H51.8
ICD-9-CM	378.87
DiseasesDB	34992
eMedicine	emerg/338
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Oculogyric crisis (OGC) is the name of a dystonic reaction to certain drugs or medical conditions characterized by a prolonged involuntary upward deviation of the eyes. The term "oculogyric" refers to the bilateral elevation of the visual gaze, but several other responses are associated with the crisis. Epilepsy can manifest as oculogyric seizures, also called versive seizures.

Drugs that can trigger an oculogyric crisis include neuroleptics (such as haloperidol, chlorpromazine, fluphenazine, olanzapine),carbamazepine, chloroquine, cisplatin, diazoxide, levodopa,lithium, , lurasidone, domperidone, nifedipine, pemoline,phencyclidine ("PCP"),reserpine, and cetirizine, an antihistamine. High-potency neuroleptics are probably the most common cause in the clinical setting.

Other causes can include postencephalitic Parkinson's, Tourette's syndrome, multiple sclerosis, neurosyphilis, head trauma, bilateral thalamic infarction, lesions of the fourth ventricle, cystic glioma of the third ventricle, herpes encephalitis, kernicterus and juvenile Parkinson's.

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