Kappa Opioid receptor
OPRK1 |
 |
Available structures |
PDB |
Ortholog search: PDBe RCSB
|
List of PDB id codes |
4DJH
|
|
|
Identifiers |
Aliases |
OPRK1, K-OR-1, KOR, KOR-1, OPRK, opioid receptor kappa 1 |
External IDs |
OMIM: 165196 MGI: 97439 HomoloGene: 20253 GeneCards: OPRK1 |
|
Targeted by Drug |
cebranopadol, hydrocodone, hydromorphone, meperidine, U50488, enadoline, GR 89696, nalbuphine, nalfurafine, salvinorin A, u-69593, tifluadom, Beta-endorphin, butorphanol, DAMGO, dihydromorphine, etonitazene, fentanyl, levomethadone, morphine, nalorphine, (-)-pentazocine, alvimopan anhydrous, buprenorphine, diprenorphine, methylnaltrexone, nalmefene, naloxone, naltrexone, naltriben, naltrindole, quadazocine, JDTic
|
|
RNA expression pattern |
 |
More reference expression data |
Orthologs |
Species |
Human |
Mouse |
Entrez |
|
|
Ensembl |
|
|
UniProt |
|
|
RefSeq (mRNA) |
|
|
RefSeq (protein) |
|
|
Location (UCSC) |
Chr 8: 53.23 – 53.25 Mb |
Chr 1: 5.59 – 5.61 Mb |
PubMed search |
|
|
|
|
4DJH
4986
18387
ENSG00000082556
ENSMUSG00000025905
P41145
P33534
NM_001282904
NM_000912
NM_001318497
NM_001204371
NM_011011
NM_001318735
NP_000903
NP_001269833
NP_001305426
NP_035141
The κ-opioid receptor (KOR) is a protein that in humans is encoded by the OPRK1 gene. The KOR is one of four related receptors that bind opioid-like compounds in the brain and are responsible for mediating the effects of these compounds. These effects include altering nociception, consciousness, motor control, and mood.
...
Wikipedia