GR-89696

GR-89696

Identifiers
IUPAC name methyl 4-[2-(3,4-dichlorophenyl)acetyl]-3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate
CAS Number	126766-32-3 Y
PubChem CID	3505
IUPHAR/BPS	1649
ChEMBL	CHEMBL277863 N
Chemical and physical data
Formula	C19H25Cl2N3O3
Molar mass	414.325 g/mol
3D model (Jmol)	Interactive image
SMILES Clc1ccc(cc1Cl)CC(=O)N2CCN(C(=O)OC)CC2CN3CCCC3
NY (what is this?)

GR-89696 is a drug which acts as a highly selective κ-opioid agonist. It shows selective effects in different animal models and it is thought it may be a subtype-selective agonist for the κ₂ subtype. Recent studies have suggested that GR-89696 and related κ₂-selective agonists may be useful for preventing the itching which is a common side effect of conventional opioid analgesic drugs, without the additional side effects of non-selective kappa agonists.