This article primarily covers the chronology of the 2015–16 Zika virus epidemic. Flag icons denote the first announcements of confirmed cases by the respective nation-states, their first deaths (and other events such as their first reported cases of microcephaly and major public health announcements), and relevant sessions and announcements of the World Health Organization (WHO), and the U.S. Centers for Disease Control (CDC), as well as relevant virological, epidemiological, and entomological studies.
The date of the first confirmations of the disease or any event in a country may be before or after the date of the events in local time because of the International Dateline.
Uganda The Zika virus is first isolated in 1947 in a rhesus monkey in the Zika Forest near Entebbe, Uganda, and first recovered from a Aedes africanus mosquito in 1948.Serological evidence indicates additional human exposure and/or presence in some mosquito species between 1951 and 1981 in parts of Africa (Uganda and Tanzania having the first detection of antibody in humans, in 1952, followed by isolation of the virus from a young girl in Nigeria in 1954 during an outbreak of jaundice, and experimental infection in a human volunteer in 1956. The virus was then found variously in Egypt, Central African Republic, Côte d'Ivoire, Senegal, Sierra Leone, and Gabon; Between 1969 and 1983, Zika was found in equatorial Asia including India, Indonesia, Malaysia and Pakistan. Zika is generally found in mosquitoes and monkeys in a band of countries stretching across equatorial Africa) and Asia (Malaysia, Philippines, Thailand, Vietnam, and Indonesia). The first confirmed case of Zika fever in a human occurs in Uganda during 1964 in a field researcher, who experiences a mild, non-itchy rash.