US 45 (WI)
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| Route information | ||||
| Maintained by WisDOT | ||||
| Length: | 305 mi (491 km) | |||
| Existed: | 1926 – present | |||
| Major junctions | ||||
| South end: |
 US 45 in Bristol
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  I-43 / WIS 100 in Hales Corners  I-41 / I-43 / I-894 in Greenfield I-94 / I-894 in West Allis US 18 in Wauwatosa WIS 175 in MilwaukeeI-41 in Germantown US 151 in Fond du LacI-41 in Oshkosh US 10 in Winchester  US 8 / WIS 47 in Monico
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| North end: |
US 45 in Land O' Lakes
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| Location | ||||
| Counties: | Kenosha, Racine, Milwaukee, Waukesha, Washington, Fond du Lac, Winnebago, Outagamie, Waupaca, Shawano, Langlade, Oneida, Vilas | |||
| Highway system | ||||
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U.S. Highway 45 (US 45) runs north–south through the eastern and northern portions of the state of Wisconsin. Also called Highway 45, it runs from the state line with Illinois near the village of Bristol in Kenosha County to the Michigan state line at the town of Land O' Lakes in Vilas County, a total of about 305 miles (491 km).
US 45 enters from Illinois at Pikeville and is a two-lane road up to its junction with WIS 36 southwest of Milwaukee. It runs concurrent with WIS 36 to its junction with WIS 100. As it follows WIS 100 north, it becomes an urban multilane road. It merges onto I-43 north in Greenfield then follows I-894, I-41, and US 41 north from the Hale Interchange one mile (1.6 km) to the east. After I-894 ends at I-94, US 45 continues as a freeway north into Wauwatosa following I-41 and US 41 north of the Zoo Interchange. The two routes split further north with US 45 continuing to West Bend. The freeway section of US 45 ends north of West Bend and continues into Kewaskum as a four-lane highway. North of Kewaskum, it passes through Waucousta and Eden as it approaches Fond du Lac
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