South Carolina Highway 340
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| Route information | ||||
| Maintained by SCDOT | ||||
| Length | 10.9 mi (17.5 km) | |||
| Major junctions | ||||
| South end |
 SC 403 near Timmonsville
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 I-20 near Florence US 52 in Darlington
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| North end |
 SC 34 in Darlington |
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| Location | ||||
| Counties | Darlington | |||
| Highway system | ||||
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South Carolina Highway 340 (SC 340) is a 10.9-mile-long (17.5 km) state highway in the U.S. state of South Carolina. The highway connects the Timmonsville area with Darlington.
SC 340 begins at an intersection with SC 403 (Oates Highway) north-northwest of Timmonsville, within Darlington County. It travels to the northeast and crosses Middle Swamp and Myrtle Branch before an interchange with Interchange 20 (I-20). It crosses over Jeffries Creek and High Hill Creek before entering the city limits of Darlington. There, it intersects U.S. Route 52 (US 52; Governor Williams Highway). It crosses some railroad tracks before it meets its northern terminus, an intersection with SC 34 (Pearl Street).
The entire route is in Darlington County.
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