Butylparaben

Butylparaben

Names
IUPAC name Butyl 4-hydroxybenzoate
Other names Butyl paraben; Butyl parahydroxybenzoate; Butyl p-hydroxybenzoate
Identifiers
CAS Number	94-26-8 Y
3D model (Jmol)	Interactive image
ChEMBL	ChEMBL459008 Y
ChemSpider	6916 Y
ECHA InfoCard	100.002.108
KEGG	D01420 Y
PubChem	7184
UNII	3QPI1U3FV8 Y
InChI InChI=1S/C11H14O3/c1-2-3-8-14-11(13)9-4-6-10(12)7-5-9/h4-7,12H,2-3,8H2,1H3 Y Key: QFOHBWFCKVYLES-UHFFFAOYSA-N Y InChI=1/C11H14O3/c1-2-3-8-14-11(13)9-4-6-10(12)7-5-9/h4-7,12H,2-3,8H2,1H3 Key: QFOHBWFCKVYLES-UHFFFAOYAN
SMILES O=C(OCCCC)c1ccc(O)cc1
Properties
Chemical formula	C11H14O3
Molar mass	194.23 g·mol−1
Appearance	Colorless, odorless, crystalline powder
Melting point	68 to 69 °C (154 to 156 °F; 341 to 342 K)
Solubility in water	Slightly soluble
Solubility in acetone, ethanol, chloroform, glycerin, propylene glycol	Soluble
Hazards
NFPA 704	1 1 0
Related compounds
Related compounds	Paraben Ethylparaben Methylparaben Propylparaben
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Y  (what is YN ?)
Infobox references

Butylparaben, or butyl p-hydroxybenzoate, is an organic compound with the formula C
4H
9O
2CC
6H
4OH. It is a white solid that is soluble in organic solvents. It has proven to be a highly successful antimicrobial preservative in cosmetics. It is also used in medication suspensions, and as a flavoring additive in food.

Members of the paraben family are found in fruit and vegetable products, such as barley, flax seed, and grapes. Butylparaben can also be found in low concentrations in liquid and solid medication suspensions, such as tylenol (acetaminophen) and ibuprofen. Butylparaben can also be found in the sewage. A 2001 study found that concentrations of parabens in Danish sewage facilities was to 100 to 1000 times below the acute or chronic effect concentrations.

Butylparaben is prepared by the esterification of 4-hydroxybenzoic acid with 1-butanol in the presence of an acid catalyst such as sulfuric acid. It is produced industrially.

Butylparaben is one of the most common bactericidal/fungicidal additives in cosmetics. It has been used in cosmetic products since the 1940s and in pharmaceutical products since 1924. The popularity of butylparaben in these products is due to its low toxicity in humans and its effective antimicrobial properties, in particular those against mold and yeast. It is now found in more than 20,000 cosmetic products including eye shadow, facial moisturizer/treatment, anti-aging cream, foundation, and sunscreen. It is also used as low-ionic strength solutions as a preservative in some foods and drugs. In most cosmetics paraben is used at low levels, ranging from 0.01 to 0.3%.