Uthman ibn Affan (Arabic: عثمان بن عفان‎, translit. ʿUthmān ibn ʿAffān‎), also known in English by the Turkish and Persian rendering, Osman, (576–17 June 656), was a companion of the Islamic prophet Muhammad and the third of the Rashidun, or "Rightly Guided Caliphs." Born into a prominent Meccan clan of the Quraysh tribe, he played a major role in early Islamic history, succeeding Umar ibn al-Khattab as caliph at age 67.

Uthman was married to Ruqayyah, and then upon her death, married Umm Kulthum, both of them being daughters of Prophet Muhammad, which earned Uthman the honorific title Dhū al-Nurayn ("He of the Two Lights").

Under the leadership of Uthman, the empire expanded into Fars (present-day Iran) in 650, and some areas of Khorasan (present-day Afghanistan) in 651. The empire's conquest of Armenia began by the 640s.

Seven years after Muhammad, Uthman was born in Ta'if to the wealthy Umayyad (Banu Umayya) clan of the Quraysh tribe of Mecca. Uthman's father, Affan, died at a young age while travelling abroad, however, Uthman was left with a large inheritance. Uthman became a merchant, like his father. His business flourished, making him one of the richest men among the Qurayshi tribe. His mother was Arwa, daughter of Um Hakim bint Abdul Mutalib, the twin sister of Abdullah, father of Muhammad, making Uthman Muhammad's first cousin. She died before 610.

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