UQCRC2

UQCRC2
Identifiers
Aliases	UQCRC2, MC3DN5, QCR2, UQCR2, ubiquinol-cytochrome c reductase core protein II
External IDs	MGI: 1914253 HomoloGene: 37764 GeneCards: UQCRC2
Gene ontology Molecular function • protein complex binding • zinc ion binding • metal ion binding • protein binding • catalytic activity • metalloendopeptidase activity Cellular component • membrane • myelin sheath • nucleoplasm • mitochondrion • respiratory chain • extracellular exosome • mitochondrial inner membrane • mitochondrial respiratory chain complex III • mitochondrial respiratory chain complex IV Biological process • proteolysis • aerobic respiration • oxidative phosphorylation • oxidation-reduction process • mitochondrial electron transport, ubiquinol to cytochrome c • protein processing involved in protein targeting to mitochondrion Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	7385	67003
Ensembl	ENSG00000284493 ENSG00000140740	ENSMUSG00000030884
UniProt	P22695	Q9DB77
RefSeq (mRNA)	NM_003366	NM_025899
RefSeq (protein)	NP_003357	NP_080175
Location (UCSC)	Chr 16: 21.95 – 21.98 Mb	Chr 7: 120.64 – 120.66 Mb
PubMed search

7385

67003

ENSG00000284493
ENSG00000140740

ENSMUSG00000030884

P22695

Q9DB77

NM_003366

NM_025899

NP_003357

NP_080175

Cytochrome b-c1 complex subunit 2, mitochondrial is a protein that in humans is encoded by the UQCRC2 gene.

Its gene product is a subunit of the respiratory chain protein (UQCR, Complex III or Cytochrome bc1 complex), which consists of the products of one mitochondrially encoded gene, MTCYTB (mitochondrial ) and ten nuclear genes: UQCRC1, UQCRC2, , UQCRFS1 (Rieske protein), UQCRB, "11kDa protein", UQCRH (cyt c1 Hinge protein), Rieske Protein presequence, "cyt. c1 associated protein", and "Rieske-associated protein".

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