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Cytochrome b is a protein that in humans is encoded by the MT-CYB gene.
Its gene product is a subunit of the respiratory chain protein (UQCR, Complex III or Cytochrome bc1 complex), which consists of the products of one mitochondrially encoded gene, MTCYTB (mitochondrial ) and ten nuclear genes: UQCRC1, UQCRC2, , UQCRFS1 (Rieske protein), UQCRB, "11kDa protein", UQCRH (cyt c1 Hinge protein), Rieske Protein presequence, "cyt. c1 associated protein", and Rieske-associated protein.