UQCRB

Identifiers

UQCRB, MC3DN3, QCR7, QP-C, QPC, UQBC, UQBP, UQCR6, UQPC, ubiquinol-cytochrome c reductase binding protein

External IDs

MGI: 1914780 HomoloGene: 38164 GeneCards: UQCRB

Gene ontology
Molecular function	• protein binding • ubiquinol-cytochrome-c reductase activity
Cellular component	• mitochondrial inner membrane • respiratory chain • membrane • mitochondrion • mitochondrial respiratory chain • mitochondrial respiratory chain complex III
Biological process	• aerobic respiration • oxidative phosphorylation • oxidation-reduction process • mitochondrial respiratory chain complex III assembly • hydrogen ion transmembrane transport • mitochondrial electron transport, ubiquinol to cytochrome c
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


7381


67530

Ensembl


ENSG00000156467


ENSMUSG00000021520

UniProt


P14927


Q9D855 Q9CQB4

RefSeq (mRNA)


NM_001199975 NM_001254752 NM_006294


NM_026219

RefSeq (protein)


NP_001186904 NP_001241681 NP_006285


NP_080495

Location (UCSC)

Chr 8: 96.23 – 96.24 Mb

Chr 13: 66.9 – 66.91 Mb

PubMed search

NM_001199975
NM_001254752
NM_006294

NM_026219

NP_001186904
NP_001241681
NP_006285

NP_080495

Ubiquinol-cytochrome c reductase binding protein, also known as UQCRB, is a protein which in humans is encoded by the UQCRB gene.

The gene product of UQCRB is a subunit of the respiratory chain protein (UQCR, Complex III or Cytochrome bc1 complex; E.C. 1.10.2.2), which consists of the products of one mitochondrially encoded gene, MTCYTB (mitochondrial ) and ten nuclear genes: UQCRC1, UQCRC2, , UQCRFS1 (Rieske protein), UQCRB, "14kDa protein", UQCRH (cyt c1 Hinge protein), Rieske Protein presequence, "cyt. c1 associated protein", and "Rieske-associated protein". After processing, the cleaved leader sequence of the iron-sulfur protein is retained as subunit 9, giving 11 subunits from 10 genes.

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