U.S. Route 412 in Missouri
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| Route information | ||||
| Maintained by MoDOT | ||||
| Length: | 50.767 mi (81.702 km) | |||
| Major junctions | ||||
| West end: |
 US 412 at Arkansas state line |
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   I-55 / I-155 / US 61 in Hayti
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| East end: |
 I-155 / US 412 at Tennessee state line |
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| Location | ||||
| Counties: | Dunklin, Pemiscot | |||
| Highway system | ||||
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U.S. Route 412 (US 412) enters the state of Missouri from Arkansas near Cardwell. The highway leaves the state into Tennessee concurrent with I-155 near Caruthersville.
US 412 enters the state from Arkansas after crossing the St. Francis River. The highway enters into the small town of Cardwell before turning to the north. In Kennett, the highway turns back to the east, concurrent with Route 84. In Hayti, US 412 has an interchange with I-55 and travels concurrent with I-155. The two highways cross the Mississippi River on the Caruthersville Bridge into Tennessee.
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