List of Interstate Highways in Missouri

Interstate Highways of the Missouri Highway System
Highway markers Interstate 44 and Interstate 435
System information
Maintained by MoDOT
Formed:	June 29, 1956 (1956-06-29)
Highway names
Interstates:	Interstate nn (I‑nn)
System links
Missouri State Highway System Interstate US State Supplemental

The Interstate Highways in Missouri are the segments of the national Dwight D. Eisenhower System of Interstate and Defense Highways that are owned and maintained by the U.S. state of Missouri.