Interstate 55 in Missouri
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| Route information | ||||
| Maintained by Missouri DOT | ||||
| Length: | 210.45 mi (338.69 km) | |||
| Existed: | 1956 – present | |||
| Major junctions | ||||
| South end: |
 I-55 at Arkansas state line |
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  I-155 / US 412 near Hayti  I-57 / US 60 in Miner US 62 in Sikeston  I-255 / I-270 in Mehlville   US 50 / US 61 / US 67 in Mehlville I-44 in St. Louis  I-64 / US 40 in St. Louis |
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| North end: |
I-55 / I-64 / US 40 / I-44 in St. Louis |
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| Highway system | ||||
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In the U.S. state of Missouri, Interstate 55 runs from the Arkansas state line to the Poplar Street Bridge over the Mississippi River in St. Louis.
Interstate 55 enters Missouri at the Arkansas border near Cooter. It runs northward through mostly flat land in the Bootheel, where it has an interchange with U.S. Route 412 and Interstate 155. The highway continues over bumpy land through or near the towns of Hayti, Portageville, and New Madrid before reaching an interchange with U.S. Route 60 and Interstate 57 just south of Sikeston. The next interchange, U.S. Route 62, provides access into the city of Sikeston and one of its most popular attractions, Lambert's Cafe, the "Home of the Throwed Rolls".
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