Trentino-Alto Adige/Südtirol (Italian: Trentino-Alto Adige, pronounced [trenˈtiːno ˈalto ˈaːdidʒe]; German: Trentino-Südtirol;Ladin: Trentin-Südtirol) is an autonomous region in Northern Italy. Since the 1970s, most legislative and administrative powers have been transferred to the two self-governing provinces that make up the region: Trentino and South Tyrol.

From the 8th century until its annexation by Italy in 1919, the region was part of Austria-Hungary and its predecessors, the Austrian Empire and the Holy Roman Empire. Together with the Austrian state of Tyrol it is represented by the Euroregion Tyrol-South Tyrol-Trentino. With a past of poverty, the region is today among the wealthiest and most developed in both Italy and the whole European Union.

In English, the region is also known as Trentino-South Tyrol or by its Italian name Trentino-Alto Adige.

The region was conquered by the Romans in 15 BC. After the end of the Western Roman Empire, it was divided between the invading Germanic tribes in the Lombard Duchy of Tridentum (today's Trentino), the Alamannic Vinschgau, and the Bavarians (who took the remaining part). After the creation of the Kingdom of Italy under Charlemagne, the Marquisate of Verona included the areas south of Bolzano, while the Duchy of Bavaria received the remaining part.

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