The Northwestern Turnpike is a historic road in West Virginia (Virginia at the time the road was created), important for being historically one of the major roads crossing the Appalachians, financed by the Virginia Board of Public Works in the 1830s. In modern times, west of Winchester, Virginia, U.S. Route 50 follows the path of the Northwestern Turnpike into West Virginia, whose major Corridor D project follows the western section of the original Northwestern Turnpike.
The following description of the Northwestern Turnpike is taken from Dr. J. M. Callahan's Semi-Centennial History of West Virginia, pages 106-9, published in 1913:
"The old Northwestern Turnpike, extending from Winchester, Virginia on a general westward course to Parkersburg, West Virginia on the Ohio, is a historic highway which deserves more mention than it has ever received as a factor related to the American westward movement and to the problem of communication between East and West. It was the inevitable result of the call of the West and the need of a Virginia state road."
"Perhaps its first suggestion was recorded by George Washington, who in 1758 had been the champion of the Braddock road (not then supposed to lie in Pennsylvania) and who in 1784 sought a route located wholly in Virginia. Returning from a visit to his western lands, after following McCulloch's Path (then the most important route across the rugged ridges between the valleys), he crossed the North Branch Potomac River on the future route of the greater Virginia highway which was partially realized in the 'state road' authorized from Winchester via Romney to Morgantown before 1786, and extended westward in 1786 by a branch road from near Cheat to Clarksburg, from which the first road was marked to the mouth of the Little Kanawha River between 1788 and 1790."