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MAO-A

MAOA
Monoamine oxidase A 2BXS.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases MAOA, MAO-A, monoamine oxidase A
External IDs OMIM: 309850 MGI: 96915 HomoloGene: 203 GeneCards: MAOA
Targeted by Drug
befloxatone, clorgiline, moclobemide, pirlindole, tranylcypromine, phenelzine
RNA expression pattern
PBB GE MAOA 204388 s at tn.png

PBB GE MAOA 204389 at tn.png

PBB GE MAOA 212741 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001270458
NM_000240

NM_173740

RefSeq (protein)

NP_000231
NP_001257387

NP_776101.3
NP_776101

Location (UCSC) Chr X: 43.65 – 43.75 Mb Chr X: 16.62 – 16.69 Mb
PubMed search

2Z5Y, 2BXR, 2BXS, 2Z5X

NM_001270458
NM_000240

NM_173740

NP_000231
NP_001257387

NP_776101.3
NP_776101

Monoamine oxidase A, also known as MAO-A, is an enzyme that in humans is encoded by the MAOA gene. This gene is one of two neighboring gene family members that encode enzymes which catalyze the oxidative deamination of amines, such as dopamine, norepinephrine, and serotonin. A mutation of this gene results in Brunner syndrome. This gene has also been associated with a variety of other psychiatric disorders, including antisocial behavior. Alternatively spliced transcript variants encoding multiple isoforms have been observed.


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Wikipedia

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