KCNQ4

KCNQ4
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2OVC, 4GOW
Identifiers
Aliases	KCNQ4, DFNA2, DFNA2A, KV7.4, potassium voltage-gated channel subfamily Q member 4
External IDs	MGI: 1926803 HomoloGene: 78107 GeneCards: KCNQ4
Targeted by Drug
ezogabine, bepridil, linopirdine, tetraethylammonium
Gene ontology Molecular function • potassium channel activity • voltage-gated ion channel activity • ion channel activity • protein binding • voltage-gated potassium channel activity Cellular component • integral component of membrane • membrane • voltage-gated potassium channel complex • plasma membrane • basal plasma membrane Biological process • regulation of ion transmembrane transport • ion transport • sensory perception of sound • potassium ion transport • inner ear morphogenesis • transmembrane transport • potassium ion transmembrane transport • transport Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	9132	60613
Ensembl	ENSG00000117013	ENSMUSG00000028631
UniProt	P56696	Q9JK97
RefSeq (mRNA)	NM_004700 NM_172163	NM_001081142
RefSeq (protein)	NP_004691 NP_751895	NP_001074611.1 NP_001074611
Location (UCSC)	Chr 1: 40.78 – 40.84 Mb	Chr 4: 120.7 – 120.75 Mb
PubMed search

2OVC, 4GOW

9132

60613

ENSG00000117013

ENSMUSG00000028631

P56696

Q9JK97

NM_004700
NM_172163

NM_001081142

NP_004691
NP_751895

NP_001074611.1
NP_001074611

Potassium voltage-gated channel subfamily KQT member 4 also known as voltage-gated potassium channel subunit K_v7.4 is a protein that in humans is encoded by the KCNQ4 gene.

The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene.

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Wikipedia