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Joseph R. Walker (December 13, 1798 — October 27, 1876) was a mountain man and experienced scout. He established the segment of the California Trail, the primary route for the emigrants to the gold fields during the California gold rush, from Fort Hall, Idaho to the Truckee River. The Walker River and Walker Lake in Nevada were named for him by John C. Frémont.
Walker was born in Roane County, Tennessee, the fourth child of seven born to Joseph and Susan Willis Walker. In 1819, the family emigrated to Missouri, settling west of Fort Osage. In 1820, he traveled to Santa Fe and was detained for a short while by Spanish authorities. He may have become one of the "Taos trappers" trapping beaver in the Spanish/Mexican territory of Alta California, then working on the Santa Fe Trail from Missouri to Santa Fe with "Old" Bill Williams. He returned to Missouri and in 1827 was appointed sheriff of Jackson County.