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Interstate 73 (I-73) is the designation for a future Interstate Highway in the U.S. state of South Carolina. When completed, it will connect the Grand Strand area with the state's interstate system.
Currently, Interstate 73 appears only as future corridor signs along SC 22, US 501, and SC 38, from the Grand Strand area to the North Carolina state line.
Authorized by the Intermodal Surface Transportation Efficiency Act of 1991 (ISTEA), Interstate 73 was established as a north-south high priority corridor from Charleston, South Carolina to Detroit, Michigan.
In 1993, the proposed route through South Carolina followed US 1 and US 52 to Florence, with 73 miles of new road in Marion and Horry Counties, and following US 17 from North Myrtle Beach to Charleston.