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Haplogroup P-P295

Haplogroup P (K2b2)
Possible time of origin 35,000 years BP
Possible place of origin Maritime South East Asia 
Ancestor K2b
Descendants P1 (P-M45) and P2 (P-B253).
(P1 is the immediate ancestor of haplogroups Q and R.)
Defining mutations P295/PF5866/S8, 92R7_1, 92R7_2, F91/PF5862/V231

Haplogroup P also known as P-P295 and K2b2 is a Y-chromosome DNA haplogroup in human genetics. P-P295 is a branch of K2b (previously Haplogroup MPS; P331) which is a branch of Haplogroup K2 (K-M526).

The only primary branches (clades) of P-P295 are P1 (P-M45) and P2 (P-B253). P1 is, in turn, the parent node of Haplogroup Q (Q-M242) and Haplogroup R (R-M207).

Basal P* is found at its highest rate among members of the Aeta (or Agta), a people indigenous to Luzon, in The Philippines. Luzon is also the only location where P*, P1* and rare P2 are now found together, along with significant levels of K2b1. Even though P1* is now more common among individuals in Eastern Siberia and Central Asia, the above distributions tend to suggest that P* (P295) emerged in South East Asia.

The major subclades Haplogroups Q and R now include most males among Europeans, Native Americans, South Asians and Central Asians.

The subclades of Haplogroup P with their defining mutation, according to the 2016 ISOGG tree:

Because P2 (P-B253) was discovered relatively recently, is not always clear if older studies have screened for it, and reported cases of basal P* (also known as P-P295*; K2b2*; PxM45, B253) may include P2.


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