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FOSL2

FOSL2
Identifiers
Aliases FOSL2, Fos-Related Antigen, FRA-2, FRA2, FOS like 2, AP-1 transcription factor subunit
External IDs MGI: 102858 HomoloGene: 3845 GeneCards: FOSL2
Gene location (Human)
Chromosome 2 (human)
Chr. Chromosome 2 (human)
Chromosome 2 (human)
Genomic location for FOSL2
Genomic location for FOSL2
Band No data available Start 28,392,448 bp
End 28,417,312 bp
RNA expression pattern
PBB GE FOSL2 205409 at fs.png

PBB GE FOSL2 218880 at fs.png

PBB GE FOSL2 218881 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005253

NM_008037

RefSeq (protein)

NP_005244

NP_032063

Location (UCSC) Chr 2: 28.39 – 28.42 Mb Chr 2: 32.14 – 32.16 Mb
PubMed search

NM_005253

NM_008037

NP_005244

NP_032063

Fos-related antigen 2 (FRA2) is a protein that in humans is encoded by the FOSL2 gene.

The Fos gene family consists of 4 members: c-Fos, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.




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