Fos-related antigen 2 (FRA2) is a protein that in humans is encoded by the FOSL2 gene.
The Fos gene family consists of 4 members: c-Fos, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.