Entactin

NID1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1NDX
Identifiers
Aliases	NID1, NID, nidogen 1
External IDs	OMIM: 131390 MGI: 97342 HomoloGene: 1878 GeneCards: NID1
Gene ontology Molecular function • laminin-1 binding • calcium ion binding • laminin binding • collagen binding • extracellular matrix binding • proteoglycan binding Cellular component • extracellular matrix • proteinaceous extracellular matrix • extracellular region • basement membrane • extracellular exosome • cell periphery • basal lamina • extracellular space Biological process • cell-matrix adhesion • extracellular matrix disassembly • extracellular matrix organization • cell adhesion • glomerular basement membrane development • basement membrane organization • positive regulation of cell-substrate adhesion Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	4811	18073
Ensembl	ENSG00000116962	ENSMUSG00000005397
UniProt	P14543	P10493
RefSeq (mRNA)	NM_002508	NM_010917
RefSeq (protein)	NP_002499	NP_035047.2 NP_035047
Location (UCSC)	Chr 1: 235.98 – 236.07 Mb	Chr 13: 13.44 – 13.51 Mb
PubMed search

1NDX

4811

18073

ENSG00000116962

ENSMUSG00000005397

P14543

P10493

NM_002508

NM_010917

NP_002499

NP_035047.2
NP_035047

Nidogen-1 (NID-1), formerly known as entactin, is a protein that in humans is encoded by the NID1 gene. Both nidogen-1 and nidogen-2 are essential components of the basement membrane alongside other components such as type IV collagen, proteoglycans (heparan sulfate and glycosaminoglycans), laminin and fibronectin.

Nidogen-1 is a member of the nidogen family of basement membrane glycoproteins. The protein interacts with several other components of basement membranes. Structurally it (along with perlecan) connects the networks formed by collagens and laminins to each other. It may also play a role in cell interactions with the extracellular matrix.

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Wikipedia