There are a number of Roman Catholic religious orders or congregations with Immaculate Conception in their name. Several of them are discussed here. There are links to articles on other ones in the "See also" section below.
Founded in 1484 at Toledo, Spain, by Saint Beatrice of Silva, sister of Blessed Amadeus of Portugal. On the marriage of Princess Isabella of Portugal with King John II of Castile, Beatrice had accompanied the queen to the court of her husband, but her great beauty having aroused the jealousy of the queen, she escaped with difficulty and took refuge in the Dominican convent at Toledo. Here for forty years she led a life of holiness, without becoming a member of the Order. Inspired by an apparition of the Virgin Mary to found a new congregation in her honour, Beatrice of Silva, with some companions, took possession of a convent (the Convent of the Order of the Immaculate Conception) set apart for them by Queen Isabella I of Castile in Toledo.
In 1489, by permission of Pope Innocent VIII, the sisters adopted the Cistercian rule, bound themselves to the daily recitation of the Office of the Immaculate Conception, and were placed under obedience to the ordinary of the archdiocese. In 1501, Pope Alexander VI united this congregation with the Benedictine community of San Pedro de las Duenas, under the Rule of St. Clare, but in 1511 Julius II gave it a rule of its own, and in 1616 special constitutions were drawn up for the congregation by Cardinal Francis Quiñones.