The Cape to Cairo Road or Pan-African Highway, sometimes called the Great North Road in sub-Saharan Africa, was a proposed road that would stretch the length of Africa, from Cape Town to Cairo, through the Cape to Cairo Red Line of British colonies. The proposal was similar to the Cape to Cairo Railway, another proposed infrastructure project through the same colonies. Neither were completed before British colonial rule ended in the colonies.
In the 1980s the plan was revived with modifications as the Cairo–Cape Town Highway, known as Trans-African Highway 4, in the transcontinental road network being developed by the United Nations Economic Commission for Africa (UNECA), the African Development Bank (ADB), and the African Union, as part of the Trans-African Highway network.
From about 1890, some in the British Empire envisioned a road that would stretch across the continent from south to north, running through the British colonies of the time, such as the Union of South Africa, Southern and Northern Rhodesia and Nyasaland, Kenya, Sudan and Egypt. The road would create cohesion between the British colonies of Africa, it was thought, and give Britain the most important and dominant political and economic influence over the continent, securing its position as a global colonial power. The road would also link some of the most important cities on the continent, including Cape Town, Johannesburg, Pretoria, Harare (then Salisbury), Lusaka, Nairobi, Khartoum and Cairo. One of the main proponents of the route was Cecil John Rhodes, though his preference was for a railway. German East Africa (Tanganyika, now Tanzania) was a gap in the British territories, but Rhodes in particular felt that Germany ought to be a natural ally. Shortly before his death he had persuaded the German Kaiser to allow access through his colony for the Cape to Cairo telegraph line (which was built as far north as Ujiji but never completed). In 1918 Tanganyika became British and the gap in territories was filled.