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Acetylcholine esterase

acetylcholinesterase
The reaction catalyzed by acetylcholinesterase.tif
Acetylcholinesterase catalyzes the hydrolysis of acetylcholine to acetate ion and choline
Identifiers
EC number 3.1.1.7
CAS number 9000-81-1
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO
ACHE
PBB Protein ACHE image.jpg
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases ACHE, AChE, acetylhydrolase, acetylcholinesterase (Yt blood group), ACEE, ARN-YT, acetylcholinesterase (Cartwright blood group), true cholinesterase (dated synonym)
External IDs MGI: 87876 HomoloGene: 543 GeneCards: ACHE
Genetically Related Diseases
type 2 diabetes mellitus
Targeted by Drug
donepezil, galantamine, neostigmine, physostigmine, pralidoxime, pyridostigmine, rivastigmine, tacrine
RNA expression pattern
PBB GE ACHE 205377 s at fs.png

PBB GE ACHE 205378 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000665
NM_001282449
NM_001302621
NM_001302622
NM_015831

NM_001290010
NM_009599

RefSeq (protein)

NP_000656
NP_001269378
NP_001289550
NP_001289551
NP_056646

NP_001276939.1
NP_033729.1
NP_001276939
NP_033729

Location (UCSC) Chr 7: 100.89 – 100.9 Mb Chr 5: 137.29 – 137.29 Mb
PubMed search

4EY7, 4PQE, 1F8U, 3LII, 4BDT, 4M0E, 4M0F, 1VZJ, 2X8B, 1B41, 4EY4, 4EY5, 4EY6, 4EY8, 5FOQ, 5HF9, 5HF6, 5FPQ, 5HF8, 5HFA


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Wikipedia

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