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5-HT4 receptor

HTR4
Identifiers
Aliases HTR4, 5-HT4, 5-HT4R, 5-HT4 receptor, 5-hydroxytryptamine receptor 4
External IDs MGI: 109246 HomoloGene: 20243 GeneCards: HTR4
Targeted by Drug
vilazodone, pathogen, 5-methoxytryptamine, α-methyl-5-HT, mosapride, renzapride, zacopride, prucalopride, RS 67333, gr-113808, piboserod, SB 204070
RNA expression pattern
PBB GE HTR4 207578 s at fs.png

PBB GE HTR4 207577 at fs.png

PBB GE HTR4 216939 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_008313

RefSeq (protein)

NP_032339.2
NP_032339

Location (UCSC) Chr 5: 148.45 – 148.68 Mb Chr 18: 62.32 – 62.47 Mb
PubMed search

NM_001286410
NM_199453

NM_008313

NP_955525

NP_032339.2
NP_032339

5-Hydroxytryptamine receptor 4 is a protein that in humans is encoded by the HTR4 gene.

This gene is a member of the family of human serotonin receptors, which are G protein-coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described, but the full-length nature of some transcript variants has not been determined.


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Wikipedia

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