2016 Karshi Challenger
| 2016 Karshi Challenger | |
|---|---|
| Date | 2 – 7 May |
| Edition | 10th |
| Draw | 32S / 16D |
| Prize money | $50,000+H |
| Surface | Hard |
| Location | Qarshi, Uzbekistan |
| Champions | |
| Singles | |
 Marko Tepavac
|
|
| Doubles | |
 Enrique López-Pérez /  Jeevan Nedunchezhiyan
|
|
The 2016 Karshi Challenger was a professional tennis tournament played on hard courts. It was the tenth edition of the tournament which was part of the 2016 ATP Challenger Tour. It took place in Qarshi, Uzbekistan between 2 and 7 May 2016.
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
The following player received entry as a lucky loser:
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