William George Tyrrell, 1st Baron Tyrrell GCB GCMG KCVO PC (17 August 1866 – 14 March 1947) was a British civil servant and diplomat. He was Permanent Under-Secretary of State for Foreign Affairs between 1925 and 1928 and British Ambassador to France from 1928 to 1934.
Tyrrell, grandson of an Indian princess, was educated in Germany (he spoke fluent German) and at Balliol College, Oxford.
Tyrrell served in the Foreign Office from 1889 to 1928. He was private secretary to the Permanent Under-Secretary of State for Foreign Affairs Thomas Sanderson from 1896 to 1903 and then secretary to the Committee of Imperial Defence from 1903 to 1904 before being appointed as second secretary at the British embassy in Rome. He returned firstly as precis-writer from 1905 to 1907 and later, with Louis Mallet, as private secretary to Sir Edward Grey from 1907 to 1915. Tyrrell supported the Entente Cordiale with France and did not think a rapprochement with Imperial Germany was possible before 1914. He appears to have been one of Grey's few intimates but an inherent laziness and frustration with red tape make an assessment of his influence difficult. Certainly however Tyrrell played a more important role than his title might suggest and, for example, in the autumn of 1913 he was sent to Washington as a personal ambassador by Grey to discuss the situation in Mexico following the overthrow of Francisco I. Madero.