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VMAT2

SLC18A2
Identifiers
Aliases SLC18A2, SVAT, SVMT, VAT2, VMAT2, solute carrier family 18 member A2
External IDs OMIM: 193001 MGI: 106677 HomoloGene: 2298 GeneCards: SLC18A2
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003054

NM_172523

RefSeq (protein)

NP_003045

NP_766111.1
NP_766111

Location (UCSC) Chr 10: 117.24 – 117.28 Mb Chr 19: 59.26 – 59.3 Mb
PubMed search

NM_003054

NM_172523

NP_003045

NP_766111.1
NP_766111

The vesicular monoamine transporter 2 (VMAT2) also known as solute carrier family 18 member 2 (SLC18A2) is a protein that in humans is encoded by the SLC18A2 gene. VMAT2 is an integral membrane protein that transports monoamines—particularly neurotransmitters such as dopamine, norepinephrine, serotonin, and histamine—from cellular cytosol into synaptic vesicles. In nigrostriatal pathway and mesolimbic pathway dopamine-releasing neurons, VMAT2 function is also necessary for the vesicular release of the neurotransmitter GABA.


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Wikipedia

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