U.S. Route 25E in Tennessee
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| Route information | |
| Auxiliary route of US 25 | |
| Length: | 114 mi (183 km) |
| Existed: | November 26, 1926 – present |
| Major junctions | |
| South end: |
   US 25 / US 25W / US 70 in Newport, TN
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US 25 / US 25W in North Corbin, KY
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| North end: |
 I-75 in North Corbin, KY
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| Location | |
| States: | Tennessee, Kentucky |
| Counties: |
TN: Cocke, Jefferson, Hamblen, Grainger, Claiborne KY: Bell, Knox, Laurel |
| Highway system | |
U.S. Route 25E is the eastern branch of U.S. Route 25 from Newport, Tennessee, where US 25 splits into US 25E and US 25W, to North Corbin, Kentucky, where the two highways rejoin. The road, however, continues as US 25E for roughly 2 miles (3.2 km) until it joins Interstate 75 in North Corbin.
All of US-25E in Tennessee is now the East Tennessee Crossings Byway, a National Scenic Byway. A portion of US 25E in Tennessee is also designated as Appalachian Development Corridor S. The corridor follows US 25E between I-81 in White Pine and State Route 63 (Corridor F) in Harrogate.
US 25E has been included in the U.S. Highway System since the system's inception in 1926.
Northbound US 25 and westbound US 70 leave Newport concurrent with one another. At an intersection west of town, US 25 splits into two highways: US 25E, which heads north from this point, and US 25W, which continues west along US 70.
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