U.S. Route 221 in Georgia
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Route of US 221 in red
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| Route information | ||||
| Maintained by GDOT | ||||
| Existed: | 1954 – present | |||
| Major junctions | ||||
| South end: |
  US 221 / SR 55 at the Florida state line southwest of Quitman
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| North end: |
US 221 at the SC line near Clarks Hill
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| Location | ||||
| Counties: | Brooks, Lowndes, Lanier, Clinch, Atkinson, Coffee, Jeff Davis, Montgomery, Treutlen, Emanuel, Johnson, Jefferson, McDuffie, Columbia | |||
| Highway system | ||||
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U.S. Route 221 (US 221) in the state of Georgia is a south–north United States Highway. It runs from the Florida border near the Quitman area to the South Carolina state line, north of Pollards Corner. The road connects North Central Florida to Upstate South Carolina.
U.S. Route 221 has concurrencies with Georgia State Route 76 from the Florida State Line to Quitman, Georgia State Route 333 within the vicinity of Quitman itself, Georgia State Route 38 from Quitman to Valdosta, Georgia State Route 7 east of Valdosta, Georgia State Route 31 from Valdosta to Douglas, Georgia State Route 135 in Lakeland and again from Douglas to Uvalda, State Route 56 from Uvalda to Gillis Springs, Georgia State Route 171 from Gillis Springs to Louisville including Georgia State Route 78 within the vicinity of Bartow, Georgia State Route 24 and Georgia State Route 4 Business in Louisville, Georgia State Route 4 from Louisville to Wrens, Georgia State Route 47 from Wrens to Pollards Corner, and Georgia State Route 150 from Pollards Corner to the South Carolina State Line.
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