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U.S. Route 221 in Florida

U.S. Highway 221 marker

U.S. Highway 221
Route information
Maintained by FDOT
Length: 39.978 mi (64.338 km)
Existed: 1930 – present
Major junctions
South end:
US 19 / US 27 Alt. / US 98 in Perry
  CR 14 at Shady Grove
US 90 in Greenville
North end: US 221 / SR 76 towards Quitman, GA
Location
Counties: Taylor, Madison, Jefferson
Highway system
SR 212 SR 222

U.S. Highway 221 marker

U.S. Route 221 (US 221) in Florida is a north–south United States Highway. It runs 40 miles (64 km) from Perry northwest to the Georgia State Line in Taylor, Madison and Jefferson Counties. The entire route is inventoried by FDOT as the northern section of unsigned State Road 55. A short overlap with US 90 exists in Greenville.

U.S. Route 221 begins in the City of Perry at the intersection of US 19-98-Alt 27 at the northern terminus of CR 361A. US Truck Route 221 also begins at this intersection, but runs along US 19-98-ALT 27. North of the terminus of CR 335, the road narrows down to two lanes at the intersection of US 27, which includes another leg of the truck detour. North of US 27, Route 221 crosses a bridge over Spring Creek and then meets a pair of at-grade crossings with railroad line owned by Georgia and Florida Railroad, which leads to a branch of the Georgia Southern and Florida Railway further north. Nearby it passes by a former Live Oak, Perry and Gulf Railroad station and then the Perry City Hall, and more than several blocks north of that point crosses another bridge over Pimple Creek just south of the intersection of County Road 356 (Ash Street). Intersections north of the city limits include County Road 359A, which is also the northern terminus of US Truck Route 221, and later County Road 361. The aforementioned G&F Railroad line meets up with the west side of US 221, but runs parallel with it throughout Taylor County, even as they both approach CR 14 (an extension of SR 14) in Shady Grove.


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