The Treaty of Greenville was signed on August 3, 1795, at Fort Greenville, now Greenville, Ohio; it followed negotiations after the Native American loss at the Battle of Fallen Timbers a year earlier. It ended the Northwest Indian War in the Ohio Country and limited strategic parcels of land to the north and west. The parties to the treaty were a coalition of Native American tribes, known as the Western Confederacy, and United States government represented by General Anthony Wayne for local frontiersmen. The treaty is considered "the beginning of modern Ohio history."
The treaty established what became known as the Greenville Treaty Line, which was for several years a boundary between Native American territory and lands open to European-American settlers. The latter frequently disregarded the treaty line as they continued to encroach on Native American lands.
The treaty also established the "annuity" system: yearly grants of federal money and supplies of calico cloth to Native American tribes and thus institutionalized continuing government influence in tribal affairs, giving outsiders considerable control over Native American life.
In exchange for goods to the value of $20,000 (such as blankets, utensils, and domestic animals), the Native American tribes ceded to the United States large parts of modern-day Ohio, the future site of downtown Chicago, the Fort Detroit area, Maumee, Ohio Area, and the Lower Sandusky Ohio Area.
The United States was represented by General "Mad Anthony" Wayne, who led the victory at Fallen Timbers. Other Americans at the treaty include William Wells, William Henry Harrison, William Clark, Caleb Swan, and Meriwether Lewis.