Sacrifice is an annual professional wrestling pay-per-view (PPV) event held by Total Nonstop Action Wrestling in the month of May. The first one was held in August 2005. When event names were shuffled by TNA for 2006, the event was moved to May. Sacrifice has had a tradition of being the final round of tournaments. Sacrifice 2005 saw Samoa Joe defeat A.J. Styles to win the Super X Cup. Sacrifice 2006 was the final round of the World X Cup Tournament. Sacrifice 2008 continued the tradition with the finals of the Deuces Wild Tag Team Tournament. Sacrifice 2009 featured Beer Money, Inc. defeating The British Invasion in the finals of the Team 3D Invitational Tag Team Tournament. All events have been held inside the Impact! Zone. On January 11, 2013, TNA announced that in 2013 will be only four PPVs, dropping Sacrifice.

Sacrifice (2006) was a professional wrestling pay-per-view (PPV) eventproduced by Total Nonstop Action Wrestling (TNA), which took place on May 14, 2006 at the Impact Zone in Orlando, Florida. It was the second event under the Sacrifice chronology. Eight matches were featured on the event's card.