TLX1

TLX1
Identifiers
Aliases	TLX1, HOX11, TCL3, T-cell leukemia homeobox 1
External IDs	MGI: 98769 HomoloGene: 4031 GeneCards: TLX1
Gene ontology Molecular function • RNA polymerase II core promoter proximal region sequence-specific DNA binding • DNA binding • sequence-specific DNA binding • transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding • protein binding Cellular component • nucleus Biological process • multicellular organism development • regulation of transcription, DNA-templated • transcription from RNA polymerase II promoter • positive regulation of transcription from RNA polymerase II promoter Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	3195	21908
Ensembl	ENSG00000107807	ENSMUSG00000025215
UniProt	P31314	P43345
RefSeq (mRNA)	NM_001195517 NM_005521	NM_021901
RefSeq (protein)	NP_001182446 NP_005512	n/a
Location (UCSC)	Chr 10: 101.13 – 101.14 Mb	Chr 19: 45.15 – 45.16 Mb
PubMed search

3195

21908

ENSG00000107807

ENSMUSG00000025215

P31314

P43345

NM_001195517
NM_005521

NM_021901

NP_001182446
NP_005512

n/a

T-cell leukemia homeobox protein 1 is a protein that in humans is encoded by the TLX1 gene, which was initially named HOX11.

TLX1 has been shown to interact with PPP1CC,PPP2CB and PPP2CA.

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Wikipedia