PPP2CA

PPP2CA
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2IAE, 2IE3, 2IE4, 2NPP, 2NYL, 2NYM, 3C5W, 3DW8, 3FGA, 3K7V, 3K7W, 3P71, 4I5L, 4I5N, 4IYP, 4LAC
Identifiers
Aliases	PPP2CA, PP2Ac, PP2CA, PP2Calpha, RP-C, protein phosphatase 2 catalytic subunit alpha
External IDs	MGI: 1321159 HomoloGene: 37660 GeneCards: PPP2CA
Gene ontology Molecular function • phosphoprotein phosphatase activity • GABA receptor binding • metal ion binding • protein C-terminus binding • protein binding • hydrolase activity Cellular component • cytoplasm • cytosol • spindle pole • membrane • microtubule cytoskeleton • plasma membrane • protein phosphatase type 2A complex • chromosome • mitochondrion • chromosome, centromeric region • cytoskeleton • extracellular exosome • nucleus Biological process • apoptotic process • regulation of transcription, DNA-templated • ceramide metabolic process • regulation of DNA replication • inactivation of MAPK activity • protein dephosphorylation • response to organic substance • positive regulation of protein serine/threonine kinase activity • regulation of Wnt signaling pathway • regulation of cell adhesion • meiotic cell cycle • negative regulation of cell growth • RNA splicing • regulation of cell differentiation • regulation of growth • mitotic nuclear envelope reassembly • nuclear-transcribed mRNA catabolic process, nonsense-mediated decay • mesoderm development • second-messenger-mediated signaling • negative regulation of epithelial to mesenchymal transition • negative regulation of tyrosine phosphorylation of STAT protein Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	5515	19052
Ensembl	ENSG00000113575	ENSMUSG00000020349
UniProt	P67775	P63330
RefSeq (mRNA)	NM_002715	NM_019411
RefSeq (protein)	NP_002706	NP_062284
Location (UCSC)	Chr 5: 134.19 – 134.23 Mb	Chr 11: 52.1 – 52.13 Mb
PubMed search

2IAE, 2IE3, 2IE4, 2NPP, 2NYL, 2NYM, 3C5W, 3DW8, 3FGA, 3K7V, 3K7W, 3P71, 4I5L, 4I5N, 4IYP, 4LAC

5515

19052

ENSG00000113575

ENSMUSG00000020349

P67775

P63330

NM_002715

NM_019411

...
Wikipedia