South Carolina Highway 641
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| Confederate Highway | ||||
| Route information | ||||
| Maintained by SCDOT | ||||
| Length: | 21.3 mi (34.3 km) | |||
| Existed: | 1932 – present | |||
| Major junctions | ||||
| West end: |
 US 301 near Allendale
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 US 321 in Sycamore US 601 near Ehrhardt
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| East end: |
 SC 64 near Lodge
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| Location | ||||
| Counties: | Allendale, Bamberg, Colleton | |||
| Highway system | ||||
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South Carolina Highway 641 (SC 641) is a primary state highway in the U.S. state of South Carolina. It provides the city of Allendale with a direct route to Charleston, via South Carolina Highway 64 and U.S. Route 17. It also serves access to Rivers Bridge State Park.
Established around 1932 as a new primary spur of SC 64 to SC 36 (today US 601). By 1938, SC 641 was extended west on new routing to SC 33/SC 331 (today US 321), in Sycamore. In 1942, its alignment was straighten, leaving Rivers Bridge Road (S-5-31/S-15-37). By 1948, SC 641 was extended west to Allendale, replacing part of SC 73. In 1952, it was extended west again to the southern boundary of the Savannah River Plant, replacing part of SC 28; reaching its apex of over 44 miles (71 km) long. Between 1968-1970, SC 641 was truncated at US 301, its former route replaced by SC 125.
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