Coordinates: 43°07′53″N 76°45′57″W / 43.13139°N 76.76583°W South Butler is a hamlet in the Town of Butler, Wayne County, New York, United States near the Savannah town line. It is located 7 miles (11 km) south-southeast of the Village of Wolcott and 5 miles (8 km) north of the hamlet of Savannah, at an elevation of 400 feet (122 m). The primary cross roads where the hamlet is located are N.Y. Route 89, South Butler Road (CR 271) and South Butler-Conquest Road (CR 275).
A United States Post Office is located in South Butler with a ZIP Code of 13154.
The hamlet was formerly known as Harringtons Corners. In 1853 at South Butler, Antoinette Brown Blackwell was the first female minister to be ordained in the United States.