SH3GL2

SH3GL2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1X03, 1X04, 2D4C, 2DBM
Identifiers
Aliases	SH3GL2, CNSA2, EEN-B1, SH3D2A, SH3P4, SH3 domain containing GRB2 like 2, endophilin A1
External IDs	MGI: 700009 HomoloGene: 20652 GeneCards: SH3GL2
Genetically Related Diseases
Parkinson's disease
Gene ontology Molecular function • protein binding • identical protein binding • lipid binding Cellular component • cytoplasm • cytosol • clathrin-coated endocytic vesicle membrane • membrane • Golgi membrane • plasma membrane • extracellular exosome • synapse • early endosome • endosome Biological process • negative regulation of epidermal growth factor receptor signaling pathway • endocytosis • antigen processing and presentation of exogenous peptide antigen via MHC class II • central nervous system development • synaptic vesicle endocytosis • regulation of receptor internalization • signal transduction • microtubule-based movement • membrane organization • synaptic vesicle uncoating • neuron projection development • dendrite extension • cellular response to brain-derived neurotrophic factor stimulus Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	6456	20404
Ensembl	ENSG00000107295	ENSMUSG00000028488
UniProt	Q99962	Q62420
RefSeq (mRNA)	NM_003026	NM_019535
RefSeq (protein)	NP_003017	NP_062408.2 NP_062408
Location (UCSC)	Chr 9: 17.58 – 17.8 Mb	Chr 4: 85.21 – 85.64 Mb
PubMed search

1X03, 1X04, 2D4C, 2DBM

6456

20404

ENSG00000107295

ENSMUSG00000028488

Q99962

Q62420

NM_003026

NM_019535

NP_003017

NP_062408.2
NP_062408

Endophilin-A1 is a protein that in humans is encoded by the SH3GL2 gene.

SH3GL2 has been shown to interact with DNM1,Amphiphysin,ADAM9,SH3KBP1 and ADAM15.

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Wikipedia