ADAM15

Identifiers

ADAM15, MDC15, ADAM metallopeptidase domain 15

External IDs

Gene ontology
Molecular function	• SH3 domain binding • metal ion binding • integrin binding • peptidase activity • protein binding • hydrolase activity • metallopeptidase activity • metalloendopeptidase activity
Cellular component	• integral component of membrane • cell projection • membrane • adherens junction • plasma membrane • cell surface • cell junction • acrosomal vesicle • extracellular exosome • cytoplasmic vesicle • endomembrane system • extracellular space
Biological process	• male gonad development • negative regulation of receptor binding • tissue regeneration • extracellular matrix disassembly • protein kinase C signaling • proteolysis • negative regulation of cell-matrix adhesion • negative regulation of cell migration • cell adhesion • negative regulation of cell growth • angiogenesis • collagen catabolic process • integrin-mediated signaling pathway • cell-matrix adhesion • innate immune response • cardiac epithelial to mesenchymal transition • apoptotic process
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


8751


11490


ENSG00000143537


ENSMUSG00000028041


Q13444


O88839

RefSeq (mRNA)

NM_001261464 NM_001261465 NM_001261466 NM_003815 NM_207191
NM_207194 NM_207195 NM_207196 NM_207197


NM_001037722 NM_009614

RefSeq (protein)

NP_001248393 NP_001248394 NP_001248395 NP_003806 NP_997074
NP_997077 NP_997078 NP_997079 NP_997080


NP_001032811.2 NP_033744.1 NP_001032811 NP_033744

Location (UCSC)

PubMed search

Disintegrin and metalloproteinase domain-containing protein 15 is an enzyme that in humans is encoded by the ADAM15 gene.