Robert Lefkowitz
| Robert Lefkowitz | |
|---|---|
Robert Lefkowitz in Stockholm 2012
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| Born | Robert Joseph Lefkowitz April 15, 1943 New York City, New York, USA |
| Nationality | United States |
| Fields | Receptor Biology Biochemistry |
| Institutions |
Duke University Howard Hughes Medical Institute |
| Alma mater | Columbia University |
| Known for |
G protein coupled receptors beta-arrestins |
| Notable awards |
National Medal of Science (2007) BBVA Foundation Frontiers of Knowledge Award (2009) Nobel Prize in Chemistry (2012) |
| Spouse | Arna Brandel (divorced) Lynn Tilley (m. 1991) |
Robert Joseph Lefkowitz (born April 15, 1943) is an American physician (internist and cardiologist) and biochemist. He is best known for his groundbreaking discoveries that reveal the inner workings of an important family G protein-coupled receptors, for which he was awarded the 2012 Nobel Prize for Chemistry with Brian Kobilka. He is currently an Investigator with the Howard Hughes Medical Institute as well as a James B. Duke Professor of Medicine and Professor of Biochemistry and Chemistry at Duke University.
Lefkowitz was born on April 15, 1943, in The Bronx, New York to Jewish parents Max and Rose Lefkowitz. Their families had immigrated to the United States from Poland in the late 19th century.
After graduating from the Bronx High School of Science in 1959, he attended Columbia College from which he received a Bachelor of Arts in chemistry 1962.
He graduated from Columbia University College of Physicians and Surgeons in 1966 with an M.D. Degree. After serving an internship and one year of general medical residency at the College of Physicians and Surgeons, he served as Clinical and Research Associate at the National Institutes of Health from 1968 to 1970.
Upon completing his medical residency and research and clinical training in 1973, he was appointed Associate Professor of Medicine and Assistant Professor of Biochemistry at the Duke University Medical Center. In 1977 he was promoted to Professor of Medicine and in 1982 to James B. Duke Professor of Medicine at Duke University. He is also a Professor of Biochemistry and a Professor of Chemistry. He has been an Investigator of the Howard Hughes Medical Institute since 1976 and was an Established Investigator of the American Heart Association from 1973-1976.
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