Proton ATPase
| hydrogen-exporting ATPase, phosphorylative mechanism | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.6.3.6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / EGO | ||||||||
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| Search | |
|---|---|
| PMC | articles |
| PubMed | articles |
| NCBI | proteins |
| Identifiers | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Symbol | E1-E2_ATPase | ||||||||
| Pfam | PF00122 | ||||||||
| InterPro | IPR000695 | ||||||||
| PROSITE | PDOC00139 | ||||||||
| TCDB | 3.A.3.3 | ||||||||
| OPM protein | 3b8c | ||||||||
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| Available protein structures: | |
|---|---|
| Pfam | structures |
| PDB | RCSB PDB; PDBe; PDBj |
| PDBsum | structure summary |
In the field of enzymology, the proton-ATPase (EC 3.6.3.6) is an enzyme that catalyzes the following chemical reaction:
The 3 substrates of this enzyme are ATP, H
2O, and H+
, whereas its 3 products are ADP, phosphate, and H+
.
This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to catalyse transmembrane movement of substances. To be specific, the protein is a part of the P-type ATPase family. The systematic name of this enzyme class is ATP phosphohydrolase (H+
-exporting).
H+
-exporting ATPase is also known as proton ATPase or more simply proton pump. Other names in common use include proton-translocating ATPase, yeast plasma membrane H+
-ATPase, yeast plasma membrane ATPase, and ATP phosphohydrolase.
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Wikipedia