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Hydrolase


In biochemistry, a hydrolase or hydrolytic enzyme is an enzyme that catalyzes the hydrolysis of a chemical bond. For example, an enzyme that catalyzed the following reaction is a hydrolase:

Systematic names of hydrolases are formed as "substrate hydrolase." However, common names are typically in the form "substratease." For example, a nuclease is a hydrolase that cleaves nucleic acids.

Hydrolases are classified as EC 3 in the EC number classification of enzymes. Hydrolases can be further classified into several subclasses, based upon the bonds they act upon:

Hydrolase secreted by Lactobacillus jensenii in the human gut stimulates the liver to secrete bile salts that aids in the digestion of food.

The word hydrolase (/ˈhdrls, -lz/) suffixes the combining form of to the hydrol syllables of hydrolysis.



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