The Potomac Conference of Seventh-day Adventists is the organizational body of the Seventh-day Adventist Church for the State of Virginia, and the Washington Metropolitan Area in the United States. Its headquarters are in Staunton, Virginia. It is a part of the Columbia Union Conference, which is one of the Unions within the North American Division of Seventh-day Adventists.
Many important Adventist sites lie within the Potomac Conference's territory, including the world headquarters of the Church in Silver Spring, Maryland, the General Conference. Housed within it is the Ellen G. White Estate, the Biblical Research Institute, and the headquarters and studios of the Hope Channel. The conference owns and runs the Washington Adventist Hospital in Takoma Park, Maryland.
A Seventh-day Adventist University, Washington Adventist University, is located within its territory. It is the holding corporation for a number of secondary institutions such as Shenandoah Valley Academy in New Market, Virginia and Takoma Academy in Takoma Park, Maryland. A number of Churches within the Potomac Conference also operate their own schools making them indirectly operated by the Conference.