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Osamu Hayaishi

Osamu Hayaishi
Native name 早石 修
Born (1920-01-08)January 8, 1920
, USA
Died December 17, 2015(2015-12-17) (aged 95)
Kyoto, Japan
Nationality Japanese
Fields Biochemistry
Institutions Osaka Bioscience Institute
Osaka Medical College
Kyoto University
Vanderbilt University
University of Tokyo
Osaka University
Washington University in St. Louis
National Institutes of Health
Alma mater Osaka University
Doctoral students Yasutomi Nishizuka
Tasuku Honjo
Shigetada Nakanishi
Known for Oxygenases
Prostaglandin
Notable awards Order of Culture (1972)
Wolf Prize (1986)

Osamu Hayaishi (早石 修 Hayaishi Osamu?, January 8, 1920 – December 17, 2015) was a prominent Japanese biochemist. He discovered Oxygenases at the National Institute of Arthritis and Metabolic Diseases, National Institutes of Health in 1955.

Hayaishi was born in , United States, in 1920. He completed his medical degree in 1942 from Osaka University. After serving as a medical officer in the Japanese Navy for 3 years, he joined the Institute of Microbial Diseases, Osaka University and was awarded his Ph.D. in 1949.

After working with Arthur Kornberg at the National Institute of Arthritis and Metabolic Diseases, National Institutes of Health and Washington University in St. Louis, Hayaishi served as a research group leader or a professor at various institutions in the US and Japan including Kyoto University, and led approximately 600 graduate students in his life including Yasutomi Nishizuka, Kunihiro Ueda, Tasuku Honjo, Shigetada Nakanishi, Akira Shimizu, and Takao Shimizu. More than 100 his pupils became professors at various universities in Japan.

Hayaishi was President of International Union of Biochemistry and Molecular Biology from 1973 to 1976.

Hayaishi is known for his great contributions to biomedical sciences and enzymology, especially the memorial discovery of Oxygenases. These enzymes are widely distributed in nature and represent a unique group of respiratory enzymes that catalyze the direct incorporation of molecular oxygen into various substrates.


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